Vajrychová Marie

Postdoctoral fellow
+420 495 832 017
marie.vajrychova@unob.cz
ORCID: 0000-0002-9495-8046

Degrees

PhD.	(2011–2018)	University of Defence, Faculty of Military Health Sciences Postgradual study programme: Biology of infection Theme of dissertation thesis: Identification of biomarkers of intraamniotic infection and fetal immune response syndrome (supervisor: PharmDr. Juraj Lenco, Ph.D., Department of Molecular Pathology and Biology; Faculty of Military Health Sciences, University of Defense, FVZ UO HK)
MSc.	(2009–2011)	University of Pardubice, Faculty of chemical technology Field of study: Analysis of biological materials Theme of diploma thesis: Development of bioactive carriers for advanced diagnosis of Alzheimer disease (supervisor: prof. RNDr. Zuzana Bilkova, Ph.D., Department of biological and biochemical sciences, Faculty of chemical technology, University of Pardubice)
Bc.	(2006–2009)	University of Pardubice, Faculty of chemical technology Field of study: Clinical biology and chemistry Theme of bachelor thesis: Clinically important kinases with focusing on GSK-3 (supervisor: Ing. Andrea Charvatova, Ph.D., Department of biological and biochemical sciences, Faculty of chemical technology, University of Pardubice)

Professional Training

2015	9th European Summer School – „Advanced Proteomics“ (Brixen, Italy)
2013/2014	Late Summer Practical Proteomics Seminar (Vienna, Austria)
2012	13^th School of mass spectrometry (Srni, Czech Republic)
2012	Basic course of statistics I (StatSoft, Prague, Czech Republic)
2012	STANAG 6001 - exam from English (level 2), LanguageTrainingCenter, Armed Forces of the CzechRepublic
2009	Professional training in the laboratory of clinical biochemistry and microbiology, Private diagnostics laboratory (Supervisor: MD. Jana Prokesova, Teplice, Czech Republic)

Research Projects

2017–2019	Czech Science Foundation: Mechanisms of IFN gamma-induced cellular senescence and phenotypic plasticity (grant no. 17-076) – member of research team
2015–2017	Czech Science Foundation: Role of oxidative stress in the interplay between cellular senescence and apoptosis (grant no. 15-03379S) – member of research team
2017	Internal grant of FNHK: HighFlow LC-MS analysis for clinical proteomics (grant no. 00179906) – member of research team
2012–2015	Internal Grant Agency of Ministry of Health of the Czech Republic: Characterization of the diagnostic potential of native polypeptides in amniotic fluid (grant no. NT/13599) – member of research team

Selected publications

Conventional-flow Liquid Chromatography-Mass Spectrometry for Exploratory Bottom-up Proteomic Analyses
Lenčo J, Vajrychová M, Pimková K, Prokšová M, Benková M, Klimentová J, Tambor V, Soukup O.
Anal Chem. 2018 Mar 27, Just Accepted Manuscript, IF (2016) 6.320

Kinase-loaded magnetic beads for sequential in vitro phosphorylation of peptides and proteins
Hromadkova L, Kupcik R, Vajrychova M, Prikryl P, Charvatova A, Jankovicova B, Ripova D, Bilkova Z, Slovakova M
Analyst, 2018, 143 (2), 466-474, IF (2016) 3,885

Microbial invasion and histological chorioamnionitis upregulate neutrophil-gelatinase associated lipocalin in preterm prelabor rupture of membranes
Vajrychova M, Kacerovsky M, Tambor V, Hornychova H, Lenco J.
J Matern Fetal Neonatal Med, 2016, 29 (1), 12-21, IF (2016) 1,826

Proteomic Analysis of Early Mid-Trimester Amniotic Fluid Does Not Predict Spontaneous Preterm Delivery
Hallingström M, Lenco J, Vajrychova M, Link M, Tambor V, Liman V, et al.
PLoS ONE, 2016, 11 (5), IF (2016) 2,806

Potential Peripartum Markers of Infectious-Inflammatory Complications in Spontaneous Preterm Birth
Tambor V, Vajrychova M, Kacerovsky M, Link M, Domasinska P, Menon R, Lenco J
BioMed Research International, 2015, č. 343501, IF (2016) 2,476

Detection of novel auto-antigens in patients with recurrent miscarriage: description of an approach and preliminary findings
Kit Y, Starykovych M, Vajrychova M, Lenco J, Zastavna D, Stoika R.
Croat Med J, 2014, 55 (3), 259-264, IF (2016) 1.619

Amniotic fluid myeloperoxidase in pregnancies complicated by preterm prelabor rupture of membranes
Kacerovsky M, Tambor V, Vajrychová M, Lenco J, Hornychova H, Musilova I, Menon R.
J Matern Fetal Neonatal Med, 2013, 26 (5), 463-468, IF (2016) 1,826