Hympánová Michaela | Centrum biomedicínského výzkumu

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Hympánová Michaela

Info

For Czech version click here

PhD student
+420 495 833 195
Michaela.hympanova@fnhk.cz
ORCID: 0000-0003-2926-3798


Michaela obtained her Master degree in 2018 at the Faculty of Pharmacy in Hradec Kralove, Charles University in Prague. Main focus of his master thesis was the Enzyme kinetic evaluation of several potential inhibitors of certain human cysteine and serine proteases. Currently, as postgraduate student at Department of Epidemiology, Faculty of Military Health and Sciences, University of Defence, focus on antimicrobial susceptibility testing, especially on microbial biofilm assays.

 

Education

PhD. (2018–today) University of Defence, Faculty of Military Health Sciences, Department of Epidemiology
study program: Medical Microbiology
Dissertation thesis title: Antimicrobial efficacy of quaternary ammonium salt
MCs. (2018) Charles University, Faculty of Pharmacy in Hradec Kralove, Department of Organic Chemistry
Diploma thesis title: Enzyme kinetic evaluation of several potential inhibitors of certain human cysteine and serine proteases


 

Professional Training

2018–today Researcher, Biomedical Research Center, University Hospital Hradec Kralove

 

Projects 

Title:

MBEC assay: The method modification for individual bacterial strains and multiple-species biofilms

Funding:

SV/FVZ2019/05

Schedule:

2019-2021

Role:

Main investigator

Title:

Oral biofilm model for susceptibility testing of disinfectants

Funding:

FNHK

Schedule:

2021

Role:

Main investigator

Title:

Development of novel quaternary ammonium compounds against microbial biofilm in oral cavity

Funding:

Healthcare Research Agency of Czech Republic

Schedule:

2019–2022

Role:

Team member

 

International Experience

9/2019–12/2019 Internship in Slovenia within the project Erasmus+, University of Ljubljana, Biotechnical Faculty, Chair of Microbiology – Prof. D. Stopar’s research group
9/2017–1/2018 Internship in Germany within the project Erasmus+, University of Bonn, Pharmaceutical Institute, Department of Pharmaceutical Chemistry – Prof. M. Gütschow’s research group

 

Publications

HYMPANOVA, Michaela, Tomas KUCERA, Jan KORABECNY a Jan MAREK, 2020. SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING. Military Medical Science Letters [online]. [vid. 2020-04-15]. ISSN 03727025, 03727025. DOI:10.31482/mmsl.2020.005

KÜPPERS, Jim, Michaela HYMPÁNOVÁ, Tim KEULER, Andreas SCHNEIDER, Gregor SCHNAKENBURG a Michael GÜTSCHOW, 2019. Transformation of the Carboxyl Group of an Amino Acid to Variously Substituted Imidazoles through a Davidson-Type Heterocyclization. Synthesis [online]. 51(09), 1961–1968. ISSN 0039-7881, 1437-210X. DOI:10.1055/s-0037-1612084

 

HYMPANOVA, Michaela, Saša TERLEP, Aneta MARKOVA, Lukáš PRCHAL, Iztok DOGSA, Lenka PULKRABKOVA, Marketa BENKOVA, Jan MAREK a David STOPAR, 2020. The Antibacterial Effects of New N-Alkylpyridinium Salts on Planktonic and Biofilm Bacteria. Frontiers in Microbiology [online]. 11, 573951. ISSN 1664-302X. Dostupné z: doi:10.3389/fmicb.2020.573951

 

SOUKUP, Ondrej, Marketa BENKOVA, Rafael DOLEZAL, Radek SLEHA, David MALINAK, Sarka SALAJKOVA, Aneta MARKOVA, Michaela HYMPANOVA, Lukas PRCHAL, Lenka RYSKOVA, Lenka HOBZOVA, Kristina SEPČIĆ, Nina GUNDE-CIMERMAN, Jan KORABECNY, Daniel JUN, Vanda BOSTIKOVA, Pavel BOSTIK a Jan MAREK, 2020. The wide-spectrum antimicrobial effect of novel N-alkyl monoquaternary ammonium salts and their mixtures; the QSAR study against bacteria. European Journal of Medicinal Chemistry [online]. 206, 112584. ISSN 0223-5234. Dostupné z: doi:10.1016/j.ejmech.2020.112584

 

TERLEP, Saša, Michaela HYMPANOVA, Iztok DOGSA, Franja PAJK a David STOPAR, 2021. Photoacoustic removal of Enterococcus faecalis biofilms from titanium surface with an Er:YAG laser using super short pulses. Lasers in Medical Science [online]. ISSN 1435-604X. Dostupné z: doi:10.1007/s10103-021-03265-6

 

 


  • Introduction
  • Our team
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    • Andrš Martin
    • Benek Ondřej
    • Benková Markéta
    • Doležal Rafael
    • Fabrik Ivo
    • Fabriková Daniela
    • Finger Vladimír
    • Górecki Lukáš
    • Hatlapatková Jana
    • Hrabinová Martina
    • Hympánová Michaela
    • Janoušek Jiří
    • Kobrlová Tereza
    • Konečný Jan
    • Korábečný Jan
    • Kuča Kamil
    • Kupčík Rudolf
    • Lenčo Juraj
    • Maliňák Dávid
    • Marek Jan
    • Marková Aneta
    • Mezeiová Eva
    • Múčková Ľubica
    • Musílek Kamil
    • Novák Martin
    • Prchal Lukáš
    • Psotka Miroslav
    • Pulkrábková Lenka
    • Schmidt Monika
    • Soukup Ondřej
    • Svobodová Barbora
    • Tichý Aleš
    • Vajrychová Marie
    • Vaňousová Andrea
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