PhD student
+420 495 833 195
Michaela.hympanova@fnhk.cz
ORCID: 0000-0003-2926-3798
Michaela obtained her Master degree in 2018 at the Faculty of Pharmacy in Hradec Kralove, Charles University in Prague. Main focus of his master thesis was the Enzyme kinetic evaluation of several potential inhibitors of certain human cysteine and serine proteases. Currently, as postgraduate student at Department of Epidemiology, Faculty of Military Health and Sciences, University of Defence, focus on antimicrobial susceptibility testing, especially on microbial biofilm assays.
| PhD. | (2018–today) | University of Defence, Faculty of Military Health Sciences, Department of Epidemiology study program: Medical Microbiology Dissertation thesis title: Antimicrobial efficacy of quaternary ammonium salt |
| MCs. | (2018) | Charles University, Faculty of Pharmacy in Hradec Kralove, Department of Organic Chemistry Diploma thesis title: Enzyme kinetic evaluation of several potential inhibitors of certain human cysteine and serine proteases |
| 2018–today | Researcher, Biomedical Research Center, University Hospital Hradec Kralove |
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Title: |
MBEC assay: The method modification for individual bacterial strains and multiple-species biofilms |
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Funding: |
SV/FVZ2019/05 |
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Schedule: |
2019-2021 |
|
Role: |
Main investigator |
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Title: |
Oral biofilm model for susceptibility testing of disinfectants |
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Funding: |
FNHK |
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Schedule: |
2021 |
|
Role: |
Main investigator |
|
Title: |
Development of novel quaternary ammonium compounds against microbial biofilm in oral cavity |
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Funding: |
Healthcare Research Agency of Czech Republic |
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Schedule: |
2019–2022 |
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Role: |
Team member |
| 9/2019–12/2019 | Internship in Slovenia within the project Erasmus+, University of Ljubljana, Biotechnical Faculty, Chair of Microbiology – Prof. D. Stopar’s research group |
| 9/2017–1/2018 | Internship in Germany within the project Erasmus+, University of Bonn, Pharmaceutical Institute, Department of Pharmaceutical Chemistry – Prof. M. Gütschow’s research group |
HYMPANOVA, Michaela, Tomas KUCERA, Jan KORABECNY a Jan MAREK, 2020. SEARCHING FOR NEW ANTIMICROBIAL AGENTS BY TARGETING BACTERIAL NAD METABOLISM: EVALUATION OF FRENTIZOLE DERIVATIVES SELECTED BY MOLECULAR DOCKING. Military Medical Science Letters [online]. [vid. 2020-04-15]. ISSN 03727025, 03727025. DOI:10.31482/mmsl.2020.005
KÜPPERS, Jim, Michaela HYMPÁNOVÁ, Tim KEULER, Andreas SCHNEIDER, Gregor SCHNAKENBURG a Michael GÜTSCHOW, 2019. Transformation of the Carboxyl Group of an Amino Acid to Variously Substituted Imidazoles through a Davidson-Type Heterocyclization. Synthesis [online]. 51(09), 1961–1968. ISSN 0039-7881, 1437-210X. DOI:10.1055/s-0037-1612084
HYMPANOVA, Michaela, Saša TERLEP, Aneta MARKOVA, Lukáš PRCHAL, Iztok DOGSA, Lenka PULKRABKOVA, Marketa BENKOVA, Jan MAREK a David STOPAR, 2020. The Antibacterial Effects of New N-Alkylpyridinium Salts on Planktonic and Biofilm Bacteria. Frontiers in Microbiology [online]. 11, 573951. ISSN 1664-302X. Dostupné z: doi:10.3389/fmicb.2020.573951
SOUKUP, Ondrej, Marketa BENKOVA, Rafael DOLEZAL, Radek SLEHA, David MALINAK, Sarka SALAJKOVA, Aneta MARKOVA, Michaela HYMPANOVA, Lukas PRCHAL, Lenka RYSKOVA, Lenka HOBZOVA, Kristina SEPČIĆ, Nina GUNDE-CIMERMAN, Jan KORABECNY, Daniel JUN, Vanda BOSTIKOVA, Pavel BOSTIK a Jan MAREK, 2020. The wide-spectrum antimicrobial effect of novel N-alkyl monoquaternary ammonium salts and their mixtures; the QSAR study against bacteria. European Journal of Medicinal Chemistry [online]. 206, 112584. ISSN 0223-5234. Dostupné z: doi:10.1016/j.ejmech.2020.112584
TERLEP, Saša, Michaela HYMPANOVA, Iztok DOGSA, Franja PAJK a David STOPAR, 2021. Photoacoustic removal of Enterococcus faecalis biofilms from titanium surface with an Er:YAG laser using super short pulses. Lasers in Medical Science [online]. ISSN 1435-604X. Dostupné z: doi:10.1007/s10103-021-03265-6
