Postdoctoral fellow
+420 495 832 502
jiri.janousek@fnhk.cz
ORCID: 0000-0002-3336-3874
Jiří obtained his Ph.D. in 2019 at the Dpt. of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University. His dissertation thesis was focus on the radiolabeling of monoclonal antibodies for in vivo tumor imaging. Currently, he is a part-time researcher at the Biomedical Research Center, University Hospital Hradec Kralove. Besides the scientific activity, he is devoted to teaching and supervising pre-gradual students at the Faculty of Pharmacy in Hradec Kralove.
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Ph.D. |
(2019) |
Charles University, Faculty of Pharmacy in Hradec Kralove |
|
PharmDr. |
(2019) |
Charles University, Faculty of Pharmacy in Hradec Kralove |
|
Mgr. |
(2014) |
Charles University, Faculty of Pharmacy in Hradec Kralove |
|
2020–present |
Biomedical Research Center, University Hospital Hradec Kralove |
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2019–present |
Assistant Professor, Dpt. of Pharmacognosy, Charles University, Faculty of Pharmacy in Hradec Kralove |
|
2014 |
Entitled to work with laboratory animals according the Law 246/1992 Sb. |
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2014–2019 |
Ph.D. student, Dpt. of Pharmacology and Toxicology, Charles University, Faculty of Pharmacy in HK |
| Title: | Radiolabeled ramucirumab for targeted radiotherapy and molecular imaging and its in vitro biological evaluation |
| Funding: | Charles University Grant Agency No. 998216/C/2016 |
| Schedule: | 2016–2019 |
| Role: | main researcher |
| 2019–present |
Lecturer of Pharmacognosy, Faculty of Pharmacy, Charles University |
| 2015–2018 |
Lecturer of Radiopharmaceuticals, Faculty of Pharmacy, Charles University |
Author or co-author of 9 scientific publications with IF
H-index: 3
(dated 03/2020)
Juhas, M., Kucerova, L., Horacek, O., Jandourek, O., Kubicek, V., Konecna, K., Kucera, R., Barta, P., Janousek, J., Paterova, P., Kunes, J., Dolezal, M., Zitko, J.: N-Pyrazinoyl Substituted Amino Acids as Potential Antimycobacterial Agents—the Synthesis and Biological Evaluation of Enantiomers. Molecules 25, article number: 1518 (2020).
BOUZ, G., JUHAS, M., PAUSAS OTERO, L., PAREDES DE LA RED, C., JANDOUREK, O., KONECNA, K., PATEROVA, P., KUBICEK, V., JANOUSEK, J., DOLEZAL, M., ZITKO, J: Substituted N-(Pyrazin-2-yl) benzenesulfonamides; Synthesis, Anti-Infective Evaluation, Cytotoxicity, and In Silico Studies. Molecules 25, article number: 138 (2020).
KRATKY, M., KONECNA, K., JANOUSEK, J., BRABLIKOVA, M., JANDOUREK, O., TREJTNAR, F., STOLARIKOVA, J., VINSOVA, J: 4-Aminobenzoic Acid Derivatives: Converting Folate Precursor to Antimicrobial and Cytotoxic Agents. Biomolecules 10, article number: 9 (2020).
JANOUSEK, J., BARTA, P., NOVY, Z., ZILKOVA, K., TREJTNAR, F: Antiangiogenic Human Monoclonal Antibody Ramucirumab Radiolabelling: In Vitro Evaluation on VEGFR2-positive Cell Lines. Anticancer Res. 39, 735-744 (2019).
VOSATKA, R., KRATKY, M., SVARCOVA, M., JANOUSEK, J., STOLARIKOVA, J., MADACKI, J., HUSZAR, S., MIKUSOVA, K., KORDULAKOVA, J., TREJTNAR, F., VINŠOVÁ, J: New lipophilic isoniazid derivatives and their 1, 3, 4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action. Eur. J. Med. Chem. 151, 824-835 (2018).
ZITKO, J., MINDLOVA, A., VALASEK, O., JANDOUREK, O., PATEROVA, P., JANOUSEK, J., KONECNA, K., DOLEZAL, M: Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents. Molecules 23, article number: 2390 (2018).
BARTA, P., JANOUSEK, J., ZILKOVA, K., TREJTNAR, F: In vitro evaluation of concentration, labeling effectiveness and stability for 131I‐labeled radioimmunoassay ligand using real‐time detection technology. J. Label. Compd. Radiopharm. 60, 80-86 (2017).
BOUZ, G., JUHAS, M., NIKLOVA, P., JANDOUREK, O., PATEROVA, P., JANOUSEK, J., TUMOVA, L., KOVALIKOVA, Z., KASTNER, P., DOLEZAL, M., ZITKO, J: Ureidopyrazine Derivatives: Synthesis and Biological Evaluation as Anti-Infectives and Abiotic Elicitors. Molecules 22, article number: 1797 (2017).
