Postdoctoral fellow
+420 495 832 017
ivo.fabrik@fnhk.cz
ORCID: 0000-0002-3027-1253
Ivo obtained his Master degree in 2010 in biochemistry at the Masaryk University in Brno. The theme of his diploma thesis was mass spectrometric analysis of oligosaccharides. In 2018 he finished postgraduate studies at the Faculty of Military Health Sciences in Hradec Kralove of the University of Defence, where he focused on a proteomic analysis of cellular signaling events occurring in dendritic cells infected by the bacterium Francisella tularensis. In 2018 he got the position of researcher in Biomedical Research Center (BRC) where he stayed until 2019. The same year he joined Anetta Härtlova’s lab at the University of Gothenburg, where he investigated phagocyte biology using proteomics. He returned to BRC in 2021 and is now a member of proteomic working group.
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Ph.D. |
(2018) |
Faculty of Military Health Sciences in Hradec Kralove, University of Defence Dissertation thesis title: Analysis of host cell proteome during the early interaction with and intracellular pathogen |
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Mgr. |
(2010) |
Masaryk University Brno, Faculty of Science Master thesis title: Characterization of carbohydrates using combination of separation techniques and mass spectrometry |
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Since 2021 |
Researcher, Biomedical Research Center, University Hospital Hradec Kralove |
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2019-2021 |
Postodctoral researcher, Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg |
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2018-2019 |
Researcher, Biomedical Research Center, University Hospital Hradec Kralove |
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2010–2018 |
PhD student, Department of Molecular Pathology and Biology, Faculty of Military Health Sciences, University of Defence |
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Title: |
The study of interaction of dendritic cells with intracellular pathogen Francisella tularensis |
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Funding: |
Grant agency Czech Republic, No. 15-02584S |
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Schedule: |
2015–2017 |
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Role: |
member of a team |
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2013 |
Award of Dean of Faculty of Military Health Sciences for research activity |
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2015 |
Nominee for a Prize of the Mayor of Hradec Kralove for research activities |
Author or co-author of 42 scientific publications with IF
H-index: 17
Citations without autocitations: 700
(dated 09/2021)
Kurzawa-Akanbi M, Tammireddy S, Fabrik I, Gliaudelytė L, Doherty MK, Heap R, Matečko-Burmann I, Burmann BM, Trost M, Lucocq JM, Gherman AV, Fairfoul G, Singh P, Burté F, Green A, McKeith IG, Härtlova A, Whitfield PD, Morris CM. Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders. Acta Neuropathol. (2021) (accepted)
Novak J, Fabrik I, Jurnecka D, Holubova J, Stanek O, Sebo P. Bordetella pertusis Acetylome is Shaped by Lysine Deacetylase Bkd1. J. Proteome Res. (2020) 19: 3680-3696.
Fabrik I, Link M, Putzova D, Plzakova L, Lubovska Z, Philimonenko V, Pavkova I, Rehulka P, Krocova Z, Hozak P, Santic M., Stulik J. The Early Dendritic Cell Signaling Induced by Virulent Francisella tularensis Strain Occurs in Phases and Involves the Activation of Extracellular Signal-Regulated Kinases (ERKs) and p38 in the Later Stage. Mol. Cell. Proteomics (2018) 17: 95–108.
Fabrik I, Link M, Hartlova A, Dankova V, Rehulka P, Stulik J. Application of SILAC Labeling to Primary Bone Marrow-Derived Dendritic Cells Reveals Extensive GM-CSF-Dependent Arginine Metabolism. J. Proteome Res. (2014) 13: 752–762.
Fabrik I, Cmelik R, Bobalova J. Analysis of free oligosaccharides by negative-ion electrospray ion trap tandem mass spectrometry in the presence of H2PO4- anions. Int. J. Mass Spectrom. (2012) 309: 88–96.
Fabrik I, Krizkova S, Huska D, Adam V, Hubalek J, Trnkova L, Eckschlager T, Kukacka J, Prusa R, Kizek R. Employment of electrochemical techniques for metallothionein determination in tumor cell lines and patients with a tumor disease. Electroanalysis (2008) 20: 1521–1532.
