Synthetic chemistry lab | Centrum biomedicínského výzkumu

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Synthetic chemistry lab

Text Aj

 

The synthetic chemistry lab is aimed to preparation of bioactive compounds via appropriate synthetic methods. The prepared compounds are further evaluated on enzymes, receptors or cell cultures. The feedback is managed through structure-activity relationship analysis between chemical structure and its biological effect. The selected bioactive compounds are subjected to molecular modelling studies in silico.

Lab performs:

  • in silico molecular modelling
  • design of compounds with targeted bioactivity
  • targeted synthesis of small molecules with assumed bioactivity
  • custom made targeted synthesis of small molecules
  • structure-activity relationship of synthesized biomolecules

 For Czech version click here


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