Postdoctoral fellow
+420 495 832 502
Marketa.Benkova@fnhk.cz
ORCID: 0000-0002-9196-9073
Markéta obtained her Master degree in 2014 in the study program Medical bioanalytics at the Faculty of Pharmacy in Hradec Kralove, Charles University in Prague. The theme of her diploma thesis was „The study of bacterial microflora at patients with spontaneous early delivery“. Currently, Markéta is a student of doctoral degree program Medical Microbiology at the Faculty of Military Health Sciences in Hradec Kralove, University of Defence in Brno, and simultaneously she works as a researcher at the Biomedical Research Center.
| Ph.D. | (2020) | University of Defence in Brno, Faculty of Military Health Sciences, study program Medical Microbiology Dissertation title: Antimicrobial susceptibility testing of newly synthesized compounds |
| MSc. | (2014) |
Charles University in Prague, Faculty of Pharmacy, study program Medical bioanalytics |
| Bc. | (2011) |
Charles University in Prague, Faculty of Pharmacy, study program Medical bioanalytics |
| 2015–today | Researcher, Biomedical Research Center, University Hospital Hradec Kralove |
| 2013–today | Laboratory technician, Biomedical Research Center, University Hospital Hradec Kralove |
| 2012–2013 | Laboratory technician, Department of Clinical Microbiology, University Hospital Hradec Kralove |
| 5/2017–7/2017 | Internship in Slovenia within the project Erasmus+, University of Ljubljana, Biotechnical Faculty, Department of Biology |
| 7/2013–9/2013 | Internship in Slovenia within the project Ceepus, University of Ljubljana, Faculty of Pharmacy, Department of Clinical Biochemistry |
Honegr, Jan; Maliňák, Dávid; Doležal, Rafael; Soukup, Ondřej; Benková, Markéta; Hroch, Lukáš; Benek, Ondřej; Janočková, Jana; Kuča, Kamil; Prymula, Roman: Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro. In: European Journal of Medicinal Chemistry, 2018, roč. 146, č. February. s. 38-46. IF 4.519.
Honegr, Jan; Doležal, Rafael; Maliňák, Dávid; Benková, Markéta; Soukup, Ondřej; de Almeida, Joyce S.F.D.; Franca, Tanos C. C.; Kuča, Kamil; Prymula, Roman: Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery. In: Molecules, 2018, roč. 23, č. 1. s. nestránkováno. IF 2.861.
Marek, Jan; Maliňák, Dávid; Doležal, Rafael; Soukup, Ondřej; Benková, Markéta; Nachtigal, Petr; Vavral, Petr; Kuča, Kamil: Novel Series of Quaternary Ammonium Surfactants Based on 2,3-Dihydro-[1,4]dioxino[2.3-b]pyridin-7-ol Ring: Synthesis, Analysis and Antimicrobial Evaluation. In: Letters in Organic Chemistry, 2018, roč. 15, č. 1. s. 3-9. IF 0.730.
Benek, Ondřej; Hroch, Lukáš; Aitken, Laura; Doležal, Rafael; Hughes, Rebecca; Guest, Patrick; Benková, Markéta; Soukup, Ondřej; Musil, Karel; Kuča, Kamil; Smith, Terry K.; Gunn-Moore, Frank; Musílek, Kamil: 6-Benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17 beta-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation. In: Medicinal Chemistry, 2017, roč. 13, č. 4. s. 345-358. IF 2.331.
Němeček, Jan; Sychra, Pavel; Macháček, Miloslav; Benková, Markéta; Karabanovich, Galina; Konečná, Klára; Kavková, Věra; Stolaříková, Jiřina; Hrabálek, Alexandr; Vávrová, Kateřina; Soukup, Ondřej; Roh, Jaroslav; Klimešová, Věra: Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents. In: European Journal of Medicinal Chemistry, 2017, roč. 130, č. April. s. 419-432. IF 4.519.
Benek, Ondřej; Soukup, Ondřej; Pasdiorová, Markéta; Hroch, Lukáš; Šepsová, Vendula; Jošt, Petr; Hrabinová, Martina; Jun, Daniel; Kuča, Kamil; Zala, Dominykas; Ramsay, Rona R.; Marco-Conteles, José; Musílek, Kamil: Design, synthesis and in vitro evaluation of indolotacrine analogues as multitarget-directed ligands for the treatment of Alzheimer's disease. In: ChemMedChem, 2016, roč. 11, č. 12, Spec. Iss.. s. 1264-1269. IF 2.980.
Boštíková, Vanda; Kuča, Kamil; Sleha, Radek; Pasdiorová, Markéta; Marek, Jan; Boštík, Pavel: Potřeba vakcíny proti Zika viru pro těhotné ženy. In: Vakcinologie, 2016, roč. 10, č. 2. s. 91-95.
Boštíková, Vanda; Hobzová, Lenka; Pasdiorová, Markéta; Marek, Jan; Prášil, Petr; Salavec, Miloslav; Sleha, Radek; Kuča, Kamil; Boštík, Pavel: Současné možnosti prevence proti nově hrozícím komáry přenášeným importovaným infekčním nákazám. In: Vakcinologie, 2016, roč. 10, č. 2. s. 85-88.
Boštíková, Vanda; Pasdiorová, Markéta; Marek, Jan; Prášil, Petr; Salavec, Miloslav; Sleha, Radek; Střítecká, Hana; Blažek, Pavel; Hanovcová, I.; Šošovičková, R.; Špliňo, M.; Smetana, J.; Chlíbek, Roman; Hytych, V.; Kuča, Kamil; Boštík, Pavel: Biologické faktory ovlivňující vybrané infekční nemoci přenášené invazivními druhy komárů. In: Klinická mikrobiologie a infekční lékařství, 2016, roč. 22, č. 2. s. 75-85.
Doležal, Rafael; Soukup, Ondřej; Maliňák, Dávid; Savedra M.L., Ranylson; Marek, Jan; Doležalová, Marie; Pasdiorová, Markéta; Salajková, Šárka; Korábečný, Jan; Honegr, Jan; Ramalho C., Teodorico; Kuča, Kamil: Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies. In: European Journal of Medicinal Chemistry, 2016, roč. 121, č. October. s. 699-711. IF 3.902.
Nepovimová, Eugenie; Korábečný, Jan; Doležal, Rafael; Nguyen, T. D.; Jun, Daniel; Soukup, Ondřej; Pasdiorová, Markéta; Jošt, Petr; Muckova, L.; Maliňák, Dávid; Górecki, Lukáš; Musílek, Kamil; Kuča, Kamil: A 7-methoxytacrine-4-pyridinealdoxime hybrid as a novel prophylactic agent with reactivation properties in organophosphate intoxication. In: Toxicology Research, 2016, roč. 5, č. 4. s. 1012-1016. IF 2.161.
Soukup, Ondřej; Doležal, Rafael; Maliňák, Dávid; Marek, Jan; Salajková, Šárka; Pasdiorová, Markéta; Honegr, Jan; Korábečný, Jan; Nachtigal, Petr; Nachon, Florian; Jun, Daniel; Kuča, Kamil: Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety. In: Bioorganic and Medicinal Chemistry, 2016, roč. 24, č. 4. s. 841-848. IF 2.923.
Karabanovich, Galina; Roh, Jaroslav; Soukup, Ondřej; Pávková, Ivona; Pasdiorová, Markéta; Tambor, Vojtěch; Stolaříková, Jiřina; Vejsová, Marcela; Vávrová, Kateřina; Klimešová, Věra; Hrabálek, Alexandr: Tetrazole regioisomers in the development of nitro group-containing antitubercular agents. In: MedChemComm, 2015, roč. 6, č. 1. s. 174-181. IF 2.319.
Marek, Jan; Maliňák, Dávid; Doležal, Rafael; Soukup, Ondřej; Pasdiorová, Markéta; Doležal, Martin; Kuča, Kamil: Synthesis and Disinfection Effect of the Pyridine-4-aldoxime Based Salts. In: Molecules, 2015, roč. 20, č. 3. s. 3681-3696. IF 2.465.
