Professor of Toxicology
+420 603 906 789
toxicology@toxicology.cz
ORCID: 0000-0002-1261-9703
Currently professor of toxicology at the University of South Bohemia in Budweis, professor emeritus of the University of Defence, Brno. He works in the field of molecular biochemistry, enzymology and toxicology of extremely poisonous synthetically prepared and natural substances and drugs. He is the author or co-author of 18 scientific monographs and textbooks, such as Military Toxicology (2004), Nutritional toxicology (2008) and others. He has published in international journals and more than 200 scientific papers and many science popularization articles. His lectures includes more than 250 titles. He is a member of several domestic and international scientific societies and editorial boards of three scientific journals.
| Mgr. | (1962) | Brno University, Faculty of Science |
| RNDr. | (1972) | Brno University, Faculty of Science |
| Ass. professor | (1993) | Military Medical Academy, Hradec Kralove |
| Professor | (2000) | Military Medical Academy, Hradec Kralove |
He works in the field of molecular biochemistry, enzymology and toxicology extremely poisonous synthetically prepared and natural substances and drugs. It deals with the development of new treatments for nerve agent poisoning and drugs for Alzheimer's disease. Beyond the research activity is devoted to the management of students, teaching and science popularization.
| 2012-present | Research worker, Biomedical Research Center (BRC), University Hospital Hradec Kralove |
| 2005-present | Professor, Department of Radiology and Toxicology, Health and Social Studies, University of South Bohemia in Budweis |
| 1964-1974 | Research worker, Department of Toxicology, Military Medical Research Institute in Hradec Kralove |
| Doctorate in Biochemistry (MU Brno) Candidature of Biochemistry (Czechoslovak Academy of Sciences, Prague). Carrier scientific qualification stage IIa (1974) | |
| 1975-1984 | Scientific and research worker, Department of Toxicology, Military Medical Research Institute in Hradec Kralove. Carrier scientific qualification stage II (1974) |
| 1984-1990 | Senior research worker, Department of Toxicology, Military Medical Academy in Hradec Kralove |
| Carrier scientific qualification grade I (1989) | |
| 1991-2000 | Lecturer in Toxicology, Department of Toxicology, Military Medical Academy in Hradec Kralove |
| 1992 | Doctor of Science in Toxicology (ASCR) |
| 2000-2005 | Professor of Toxicology, Department of Toxicology, Military Medical Academy in Hradec Kralove |
| 1990 | Hungarian Academy of Sciences, Department of Biochemistry, Budapest, Hungaria (4 weeks) |
| 1992 | Military Medical Academy, Sofia, Bulgaria (2 weeks) |
| Title: | GA306/95/0268 - Úloha metabolitů arginin vasopresinu a některých dalších peptidů v učení a paměti podmíněných ovlivněním cholinergního přenosu (1995-1997, GA0/GA) |
| Funding: | Grantová agentura České republiky |
| Schedule: | 1995 -1997 |
| Role: | Team leader |
He has published more than 540 scientific papers and presented more than 200 lectures and posters on scientific meetings. Author and co-author of 18 books and/or textbooks, e.g. Military Toxicology (Grada, Prague 2004) or chapters in monograph, e.g. Handbook of the Toxicology of Chemical Warfare Agents (Academic Press/Elsevier 2009). More than 3000 citations to SCI and more than 4585 to Google Scholar Citations, Hirsch-index = 32, i10 index = 91. Co-Editor of the Journal of Applied Biomedicine, the member of Editorial board of Military Medical Science Letters, Pharmaceutical Design and Current Perspectives, and Kontakt. His scientific work focuses on the biochemical mechanisms of toxic action of different biologically active compounds, mainly on inhibition of cholinesterases, include their application as Alzheimer's disease drugs and on the function of centrally active anticholinesterases and different peptides in teaching and memory processes. He follow to popularization of science and published hundreds of articles in specialized journals and newspapers – Vesmír, Živa, Zdravotnické noviny, MF Dnes, Lidové noviny and other. He is engaged Internet server TOXICOLOGY (http://www.toxicology,cz) much-frequented by students and persons concerned in toxicology.
(dated 04/2020)
Patočka J. Cynomorium plants: Bioactive compounds and pharmacologic action. Milit Med Sci Lett. 2020; 89(1):
Navrátilová Z, Patočka J. Bazalka pravá (Ocimum basilicum L.) a její účinky na nervový systém. Psychiatrie 2020; 24(1): 24-28.
Patočka J, Wu Q, Nepovímová E, Kuča K. Phenytoin – An anti-seizure drugs: Overview of its chwemistry, pharmacology and toxicology. Food Chem Toxicol. 2020; K dispozici online 4. května 2020, 111393. IF = 3.775
Patočka J. Strychnine. In. Gupta RC (ed.) Handbook of Toxicology of Chemical Warfare Agents, Third Edition. Chapter 16. San Diego: Elsevier Inc. Academic Press, 2020: 239-248. ISBN 978-0-12-619090-6
Patočka J, Nepovímová E, Wu W Kuca K. Digoxin: Pharmacology and Toxicology – a Review. Environ Toxicol Pharmacol. Pub Date : 2020-05-07 , DOI: 10.1016/j.etap.2020.103400 IF = 3.061
Strunecká A, Navrátilová Z, Patočka J. Léčivé byliny a duševní zdraví. 2. Upravené vydání. ProfiSales s r.o. 2019, 226 stran. ISBN 978-80-87494-34-9
Wu Q, Patocka J, Nepovimova E, Kuca K. Jatropha Gossypiifolia L. and its biologically active metabolites: A mini review. J Ethnopharmacol. 2019 IF = 3,414
Navratilova Z, Patocka J. Meduňka lékařská (Melissa officinalis L.) a její účinky na nervový systém. Psychiatrie 2019; 23(1):
Patočka J. Evidence-based toxicology: where does it go? Milit Med Sci Lett 2019; 88(1):
Wu Q, Patocka J, Kuca K. Beauvericin, a Fusarium mycotoxin: Anticancer activity, mechanisms, and human exposure risk assessment. Mini-Rev Med Chem. 2019; 19(3): 206-214. IF = 2,842
Patocka J, Navratilova Z. Achillea fragrantissima: Pharmacology review. Clin Oncol. 2019; 4: 1601. IF = 3.047
Patocka J. Carphedon at the crossroads: A dangerous drug or a promising psychopharmaceutical? Glob J Pharmaceu Sci. 2019; 7(3): 555713. DOI: 10.19080/GJPPS.2019.07.555713002
Navratilova Z, Patocka J. Gardenia jasminoides a její účinky na nervový systém. Psychiatrie 2019; 23(2): 88-92.
Patocka J, Navratilova Z. Bioactivity of Lilium candidum L: A mini review. Biomed J Sci & Tech Res 2019; 18(5). BJSTR. MS.ID.003204. IF = 0,548
Patocka J. Perfluoroisobutene: Poisonous choking gas. Milit Med Sci Lett. 2019, 88(3): 98-105.
Patocka J, Navratilova Z, Krejcar O, Kuca K. Coffee, caffeine and cognition: a Benefit or disadvantage? Lett Drug Design Disc. 2019; 16: DOI: 10.2174/1570180816666190620142158. IF = 0,789
Patocka J. Will the sulphur polypore (Laetiporus sulphureus) become a new functional food? Glob J Medical Clin Case Rep 2019; 6(1): 006-009
Patocka J, Navratilova Z. D-Serin: Od kuriózní molekuly k potenciálnímu psychofarmaku. Psychiatrie 2019; 23(3): 142-147.
Patocka J, Navratilova Z. Bioactivity of Echium amoenum: A mini review. Biomed J Sci & Tech Res 2019; 18(5): 14915-14917. BJSTR. MS.ID.003204. IF = 0,548
Patocka J. Highly toxic ribosome-inactivating proteins as chemical warfare or terrorist agents. Int Rev Armed Forces Med Services 2019; 92(3):
Navratilova Z, Patocka J. Rozmarýn lékařský (Rosmarinus officinalis L.) a jeho účinky na nervový systém. Psychiatrie 2019; 23(4): 141-146.
